Orofacial Granulomatosis among Pediatric Patients Well Controlled by Corticosteroid Treatment: A Rare Case Series

Figure 1

Clinical and pathological characteristics of four pediatric patients with orofacial granulomatosis. (a) Each showed bleeding edema with upper anterior gingival redness. (b) Incision biopsy demonstrated noncaseating granuloma with infiltrating lymphocytes, plasmacytes, epithelioid histocytes, and multinucleated giant cells beneath the mucosal epithelium (patient #1 and 3: magnification 400x; #2 and 4: magnification 200x). (c) Local or systemic corticosteroid treatment improved oral manifestation.