Suicidality and Illness Course Worsening in a Male Patient with Bipolar Disorder during Tamoxifen Treatment for ER+/HER2+ Breast Cancer

Table 1

Patient MADRS, HAM-D, and Q-LES-Q-SF scores at second hospitalization, discharge, and one-year follow-up.

	MADRS range 0-50	HAM-D range 0-60	Q-LES-Q-SF (% maximum) range 14-70 (0–100%)
Hospitalization	36	28	28 (25%)
Discharge (Tamoxifen interruption)	26	19	34 (47%)
15 days after discharge	15	9	45 (53%)
30 days after discharge	10	3	52 (68%)
60 days after discharge	3	1	63 (88%)
100 days after discharge	3	1	65 (91%)
365 days after discharge	2	1	67 (95%)

MADRS score: 0-6 = normal; 7-19 = mild depression; 20-34 = moderate depression; 34-60 = severe depression. Ham-D score: 0-7 = normal; 8-13 = mild depression; 14-18 = moderate depression; 19-22 = severe depression; 23-50 = very severe depression.