Clinical Diagnosis of an Autoimmune Encephalitis Presented as a Manic Episode with Psychotic Symptoms: A Case Report

Table 3

Results of blood tests, serology, and autoimmunity.

TEST	Abnormal results	Normal results
Blood test	CBC: leukocytes /μL, neutrophils (count) /μL, neutrophils (percentage) 79.62%, lymphocytes (percentage) 12.01%; Biochemistry: gamma-glutamyltransferase 110 U/L, alanine transaminase 81 U/L; C-reactive protein 8.5 mg/L	Vitamins including B12, folic acid and vitamin D, and the rest of results of CBC and biochemistry; Normal thyroid profile; Normal clotting
Serology (obtained 5 days after analytical extraction)	—	Negative for active infection of syphilis, cytomegalovirus, human immunodeficiency virus, hepatitis B and C virus, herpes simplex virus 1 and 2, and varicella-zoster virus.
Autoimmunity	Weak positive for antinuclear antibodies (1/80) with a speckled pattern.	Immunoglobulin A, G, M, complement C3 and C4; Negative for antibodies: (i) Anti-double-stranded DNA; (ii) Extractable nuclear antigen (including anti-RNP UI (70 kDa+A+C), anti Sm, anti-SSA/Ro, anti-SSB/La, anti-Scl-70, anti-Jo-1); (iii) Anticardiolipin; (iv) Anti-beta-2-glycoprotein I; (v) Antineutrophil cytoplasm; (vi) Antitransglutaminase; (vii) Antithyroid peroxidase; (viii) Anticyclic citrullinated peptide; (ix) Rheumatoid factor; (x) Antineuronal (intracellular antigen): antiamphiphysin, antineuronal-CV2, anti Ma1, anti Ma2, anti-Hu, Ac anti-Ri, anti-Yo, anti-GAD; (xi) Anti-NMDAR