ECT-Resistant Bipolar Depression Treated with a Single Course of Triple Chronotherapy

Figure 1

Triple chronotherapy protocol used in this case. -axis shows the days of the protocol; -axis is time of day. A night of total sleep deprivation (day 1) is followed by phase advanced reintroduction of sleep (patient asleep at 6 PM following sleep deprivation, advancing the next night to 8 PM, and so on). 30 minutes of bright light was administered each morning at 7 AM.