Loxapine in the Treatment of Manic and Psychotic Symptoms in an Individual Intolerant to Multiple Mood-Stabilizing and Antipsychotic Medications

Table 2

Vital sign values with antipsychotics during our patient’s admission.

Antipsychotic	Hospital day (HD)	Dose	Temperature (degrees Celsius)	Blood pressure (systolic in mmHg/diastolic in mmHg)	Heart rate (beats per minute)
Risperidone	20	1 mg QHS	36.8	136/65	117
	21	1 mg QHS	36.9	109/59	88
	22	2 mg QHS	36.8	119/77]	98
	23	3 mg QHS	37.4	108/66	109
	24	4 mg QHS	Pt refused	118/69	122
	25	4 mg QHS	Pt refused	Pt refused	Pt refused
	26	4 mg QHS	36.8	137/83	102
	27	5 mg QHS	36.7	105/71	111
	28	6 mg QHS	36.9	104/59	104
	29	6 mg QHS	36.8	110/70	107
	30	6 mg QHS	36.6	115/50	130
	31	6 mg QHS	Pt refused	102/55	126
	32	6 mg QHS	37.1	116/64	89
	33	6 mg QHS	36.7	139/57	114
	34	6 mg QHS	Pt refused	113/63	112
	35	6 mg QHS	37	116/76	88
	36	6 mg QHS	Pt refused	Pt refused	Pt refused
	37	6 mg QHS	36.6	110/55	106
	38	6 mg QHS	36.9	116/68	94
	39	6 mg QHS	36.5	104/69	112
	40	6 mg QHS	36.5	113/62	92
	41	6 mg QHS	36.9	107/60	103
	42	6 mg QHS	36.5	104/62	91
	43	6 mg QHS	36.7	117/63	103
	44	6 mg QHS	36.7	133/57	100
	45	6 mg QHS	37	112/69	79
	46	6 mg QHS	37	111/67	99
	47	6 mg QHS	36.7	112/60	89
	48	6 mg QHS	36.7	134/89	109
	49	6 mg QHS	36.5	107/57	110
	50	6 mg QHS	36.9	107/63	80
	51	6 mg QHS	36.8	102/58	89
	52	6 mg QHS	36.9	123/61	112
	53	6 mg QHS	36.9	80/53	128
	54	6 mg QHS	38.9	93/52	97
	55	6 mg QHS	39.1	96/50	110
	56	6 mg QHS	39.6	99/50	126
	57	6 mg QHS	36.9	98/52	102
	58	6 mg QHS	37.3	85/52	107
	59	6 mg QHS	37.5	92/50	105
	60	6 mg QHS	37.1	97/41	106
	61	6 mg QHS	37.4	108/41	107
	62	6 mg QHS	37.1	97/52	111
	63	6 mg QHS	39.5	90/42	121
	64	(held)	39.5	94/47	156
	65	(held)	38.3	99/57	90
	66	(held)	38.2	97/55	90
	67	(held)	38.2	89/52	82
	68	(held)	38	88/53	80
Clozapine	69	6.25 mg QHS	37.2	93/54	77
	70	12.5 mg QHS	36.5	135/90	103
	71	12.5 mg BID	37.6	107/57	96
	72	12.5 mg BID	36.6	118/60	89
	73	12.5 mg BID	36.8	103/58	86
	74	25 mg QPM	Pt refused	Pt refused	Pt refused
	75	12.5 mg QAM, 25 mg QHS	36.6	102/61	74
	76	25 mg BID	36.7	106/63	75
	77	25 mg BID	36.5	136/83	147
	78	25 mg BID	36.5	102/55	84
	79	25 mg BID	37.1	94/52	69
Loxapine	80	10 mg QHS	36.7	109/64	68
	81	10 mg QHS	36.4	107/59	80
	82	10 mg QHS	36.5	112/58	98
	83	10 mg BID	37.2	114/66	95
	84	10 mg QAM, 20 mg QHS	36.7	111/64	88
	85	10 mg QAM, 20 mg QHS	36.4	95/54	82
	86	20 mg BID	36.7	114/67	104
	87	20 mg BID	36.4	117/69	85
	88	20 mg BID	36.7	101/51	97
	89	20 mg BID	36.7	111/62	88
	90	20 mg BID	36.7	161/100	134
	91	20 mg BID	36.6	110/72	108
	92	20 mg BID	37.1	99/64	125
	93	20 mg BID	36.9	127/76	112
	94	20 mg BID	36.9	127/61	100
	95	20 mg BID	36.7	118/71	117
	96	20 mg BID	36.3	127/80	82
	97	20 mg BID	36.8	120/82	110
	98	50 mg QHS	36.5	118/85	92
	99	50 mg QHS	36.8	135/71	102
	100	50 mg QHS	36.8	122/73	64
	101	50 mg QHS	36.5	130/79	101
	102	50 mg QHS	36.6	138/90	108
	103	50 mg QHS	Pt refused	Pt refused	Pt refused
	104	50 mg QHS	37.4	133/79	97
	105	50 mg QHS	37.8	135/97	120
	106	50 mg QHS	36.8	128/94	98
	107	50 mg QHS	36.1	129/90	88
	108	50 mg QHS	36.7	144/75	100
	109	50 mg QHS	37	123/79	103
	110	50 mg QHS	37.1	114/67	93
	111	50 mg QHS	36.8	132/75	88
	112	50 mg QHS	37	109/80	99
	113	50 mg QHS	36.8	128/78	93
	114	50 mg QHS	36.4	143/69	112
	115	50 mg QHS	36.7	121/68	104
	116	50 mg QHS	Pt refused	Pt refused	Pt refused
	117	50 mg QHS	37.1	132/73	103
	118	50 mg QHS	36	142/78	101
	119	50 mg QHS	36.8	132/71	110
	120	50 mg QHS	36.5	119/68	88
	121	50 mg QHS	36.6	106/64	99
	122	50 mg QHS	36.9	123/84	108
	123	50 mg QHS	36.5	120/72	101
	124	50 mg QHS	36.6	157/78	79
	125	50 mg QHS	37.9	111/67	102
	126	50 mg QHS	Pt refused	Pt refused	Pt refused
	127	50 mg QHS	37.1	115/80	109
	128	50 mg QHS	Pt refused	118/67	106
	129	50 mg QHS	Pt refused	Pt refused	Pt refused
	130	50 mg QHS	36.1	130/71	95
	131	50 mg QHS	36.7	176/73	122
	132	25 mg QAM, 50 mg QHS	Pt refused	Pt refused	Pt refused
	133	25 mg QAM, 50 mg QHS	37.2	106/63	114
	134	50 mg BID	36.7	105/65	116
	135	50 mg BID	36.6	108/66	115
	136	50 mg BID	36.9	123/88	113
	137	50 mg BID	36.7	136/81	102
	138	50 mg BID	36.8	148/75	98
	139	50 mg QAM, 75 mg QHS	Pt refused	Pt refused	Pt refused
	140	50 mg QAM, 75 mg QHS	36.9	123/88	113
	141	50 mg QAM, 75 mg QHS	36.7	136/81	102
	142	50 mg QAM, 75 mg QHS	36.5	115/59	103
	143	50 mg QAM, 75 mg QHS	Pt refused	Pt refused	Pt refused
144	50 mg QAM, 75 mg QHS	36	124/84	123
145	50 mg QAM, 75 mg QHS	36.6	132/62	89

mg: milligrams; mmHg: millimeters of mercury; pt: patient; QHS: at bedtime; QAM: every morning; BID: twice daily.