Pulmonary Artery Intimal Sarcoma Diagnosed Preoperatively by Endovascular Biopsy and Treated via Right Pneumonectomy and Pulmonary Arterioplasty

Figure 4

Histopathology of intimal sarcoma (×200). (a) Hematoxylin and eosin stain showing atypical spindle-shaped tumor cells. (b) Immunohistochemical staining showing positive staining for murine double minute type 2 homologue. (c) Immunohistochemical staining showing positive staining for vimentin. (d) Immunohistochemical staining showing positive staining for alpha smooth muscle actin. (e) Immunohistochemical staining showing negative staining for desmin. (f) Elastica-van-Gieson staining showed tumor cells invading outside pulmonary artery. Arrows indicate that the wall of pulmonary artery was destroyed by tumor invasion.

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