Doxycycline-Induced Antinuclear Antibody and Antineutrophil Cytoplasmic Antibody Associated Vasculitis: A Case Report and Literature Review

Figure 1

Representative images of histological/pathological findings in a renal biopsy specimen from the patient. (a) Jones silver stain shows a glomerulus in a relatively normal morphology, with no crescents or necrosis noted; adjacent is an arterial with medial hypertrophy. (b) An arterial and PAS stain shows marked intimal thickening/fibrosis. (c) Jones silver stain demonstrates an artery with fibrous obliteration/complete luminal occlusion. (d) H&E stain shows focal intraluminal neutrophilic casts/debris in the tubules, which can be seen in infections or other types of tubular interstitial nephritis. No immune complexes were present in the glomeruli.