Case Report
A Case of Granulomatosis with Polyangiitis with Various Breast Lesions as the Initial Symptoms: A Case-Based Review
Table 1
Clinical characteristics of 35 cases of breast lesions with GPA.
| | Mean age ± SD years | 49 ± 14 (28–81) |
| | Gender | Male: 2, female: 33 |
| | ANCA | PR3(C)-ANCA: 10 | | Negative: 4 | | Not described: 21 |
| | Location of breast lesion | Bilateral: 7 | | Unilateral: 28 (right: 18, left: 9, unknown: 1) |
| | Formation of breast lesion | Nodule/tumor: 31 | | Ulceration: 6 | | Discharge from nipples: 1 |
| | Onset of breast lesion | Initial symptom: 19 | | Onset after GPA diagnosis: 15 |
| | Pathology of breast lesion | Necrotizing granulomatous vasculitis: 25 | | Granulomatous mastitis: 4 | | Others (inflammation with giant cells, panniculitis): 5 |
| | Treatment | Corticosteroid: 28 | | Cyclophosphamide: 16 | | Rituximab: 4 |
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