Case Report
A Case of Granulomatosis with Polyangiitis with Various Breast Lesions as the Initial Symptoms: A Case-Based Review
Table 1
Clinical characteristics of 35 cases of breast lesions with GPA.
| Mean age ± SD years | 49 ± 14 (28–81) |
| Gender | Male: 2, female: 33 |
| ANCA | PR3(C)-ANCA: 10 | Negative: 4 | Not described: 21 |
| Location of breast lesion | Bilateral: 7 | Unilateral: 28 (right: 18, left: 9, unknown: 1) |
| Formation of breast lesion | Nodule/tumor: 31 | Ulceration: 6 | Discharge from nipples: 1 |
| Onset of breast lesion | Initial symptom: 19 | Onset after GPA diagnosis: 15 |
| Pathology of breast lesion | Necrotizing granulomatous vasculitis: 25 | Granulomatous mastitis: 4 | Others (inflammation with giant cells, panniculitis): 5 |
| Treatment | Corticosteroid: 28 | Cyclophosphamide: 16 | Rituximab: 4 |
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