Sensory-Motor Polyneuropathy and Digital Ischemia: A Rare Presentation of Granulomatosis with Polyangiitis

Table 1

Summary of investigations.

Investigation	Value	Reference range
White cell count	9300	4,000–11,000 cells/μL
Neutrophils	6600	2,000–7,000 cells/μL
Lymphocytes	1120	1,000–4,000 cells/μL
Hemoglobin	12.0	12–16 g/dL
Platelets	177,000	150,000–450,000/μL
Blood film	No abnormal cells seen. Within normal limits
Serum creatinine	65	70–110 μmol/L
Sodium	136	135–145 mmol/L
Potassium	4.2	3.5–4.5 mmol/L
AST	20	<40 U/L
ALT	25	<35 U/L
Albumin	35	35–45 g/L
Globulin	38	30–40 g/L
ALP	106	30–120 U/L
ESR	110	<20 mm/1st hour
CRP	36	<6 mg/L
Rheumatoid factor	<8	<8 IU/L
Antinuclear antibodies	Negative
HIV 1 and 2 antigens/antibodies	Negative
c-ANCA	Positive
p-ANCA	Negative
Anti-Smith antibody	Negative
Anti-Scl-70 antibody	Negative
Anti-Ro antibody	Negative
Anti-La antibody	Negative
Lupus anticoagulant	Negative
Anticardiolipin antibody, IgM	Negative
Anti-ß2 glycoprotein antibodies, IgM and IgG	Negative
Serum complement level	Normal
Serum cryoglobulin	Negative
Hepatitis C antibody	Negative
Hepatitis B surface antigen	Negative
Urine full report	Normal
Chest X-ray	No abnormality detected
Ultrasound abdomen	Normal
2D echocardiogram	No abnormality detected including any cardiac source of emboli
HbA1C	6.0%

AST, aspartate transaminase; ALT, alanine transaminase; ALP, alkaline phosphatase; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; TSH, thyroid stimulating hormone; HIV, human immunodeficiency virus; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibody; p-ANCA, perinuclear antineutrophil cytoplasmic antibody.