Autoinflammatory/Autoimmunity Syndrome Induced By Adjuvants (ASIA) Due to Silicone Incompatibility Syndrome

Table 1

Laboratory values.

Laboratory studies	Results	Reference values
Inflammatory markers
C-reactive protein	10.73 mg/dL	0.00–5.00 mg/dl
Immunological
Antinuclear antibodies (ANA) HEp-2-IF	Positive 1: 640, centromeric pattern to immunofluorescence	Positive ≥ 1 : 40
Anti-DNA ds, IF	Negative	Positive ≥ 1 : 10
Antimicrosomal antibodies (TPO)	0.44 IU/ml	0.00–4.61
Interleukin-6 (IL-6)	4.30 pg/ml	0–6.50 pg/ml
Sclero-70 antibodies	46.67 U	<20: negative; 20–39: positive-weak; 40–80: positive-moderate; >80: positive-strong
Anti-SSB (LA) (ELISA)	1.86 U	<16: negative; 16–20: equivocal; >20: positive
Anti-SM (ELISA)	7.06 U	<20: negative; 20–39: positive-weak; 40–80: positive-moderate; >80: positive-strong
Anti-RNP (ELISA)	5.00 U	<20: negative; 20–39: positive-weak; 40–80: positive-moderate; >80: positive-strong
Anti-JO	3.60 U	<20: negative; 20–39: positive-weak; 40–80: positive-moderate; >80: positive-strong
Rheumatoid factor- nephelometry	<20.0 IU/mg	0.00–20.0 IU/mg
Citrullinated cyclic peptide antibody	0.60 U/mL	Positive: <5.0 U/mL
Total vitamin D	25.80 ng/ml	≥30 ng/dl
Antithyroglobulin antibodies	5.48 IU/ml	<4.5 UI/mL
Complement C3 nephelometry	115.00 mg/dL	79.00–152.00 mg/dL
Complement C4 nephelometry	21.60 mg/dL	16.00–38.00 mg/dL
Hormonal Profile
Intact parathyroid hormone	80 pg/mL	18–116 pg/mL
TSH- thyroid stimulating hormone	0.7273 uUI/mL	Adults: 0.35–4.95
T4- total thyroxine	7.57 μg/dL	Adults: 4.90–11.70
T3- total triiodothyronine	1.19 nmol/L	Adults: 0.89–2.44
Virology
Hepatitis delta IgM (EIA)	Negative
HBsAg- hepatitis B surface antigen	Not reactive
HBcAc- hepatitis B, anticore IgG/IgM	Not reactive
Hepatitis C, antibodies	0.03	Reactive > 1