Glomerulonephritis and Interstitial Nephritis Originating from Vasculitis of the Interlobular Arteries of the Kidney in a Patient with Eosinophilic Granulomatosis with Polyangiitis

Figure 1

(a) Renal biopsy showing remarkable infiltration of eosinophils in the interstitium of the kidney (scale bar: 100 μm). (b) Fibrinoid necrosis visible in the interlobular arteries of the kidney (scale bar: 50 μm). (c) One glomerulus, showing glomerular crescent formation (scale bar: 50 μm). (d) Rupture of the glomerular basement membrane in this glomerulus, which appears to have spread from outside of the glomerulus; the yellow arrows indicate infiltration from the interstitium (scale bar: 50 μm). A B: haematoxylin and eosin staining, C D: periodic acid methenamine silver staining).