A Case of SAPHO Syndrome Complicated by Uveitis with Good Response to Both TNF Inhibitor and JAKinib

Table 2

The comparison of different other studies with the present case report is depicted.

Study	Arias-Santiago et al. [17]	Vekic et al. [18]	Garcovich et al. [15]	Castellví et al. [19]	Present case
Patient	49 year female	26 year male	25 year male	28 year female	18 year male
Presentation	Axial involvement, PPP	Axial and peripheral arthritis, HS, PG	Severe acne, axial (SCJ, SI joint)	Axial with cutaneous (PPP)	Sterile osteitis, acne, PPP, uveitis
Biologic used	ADA	ADA	ADA	ADA	ADA
Response to ADA	Excellent response to cutaneous and osteoarticular	Improvement in both cutaneous and articular	Bony involve rapidly improved, acne improving with residual scarring, improved QOL	Both improved	Improvement in VAS, bony, cutaneous, and ocular symptoms
Other treatment	Infliximab—no response to cutaneous	Methotrexate	Methotrexate, isotretinoin	SAAZ,	SAAZ, methotrexate, later tofacitinib
Follow-up	10 month	9 months	24 months	18 months	Follow-up for 3 years—defaulted in between

PPP: palmoplantar pustular psoriasis, SAAZ: sulfasalazine, ADA: adalimumab, HS: hidradenitis suppurativa, PG: pyoderma gangrenosum, QOL: quality of life, SCJ: sternoclavicular joint, SI: sacroiliac joint, VAS: visual analogue scale.