Mediastinal Teratoma with Neuroendocrine Features in 34-Year-Old Male with Syncope

Figure 3

Mediastinal tumor weighed 165 g with smooth outer surface and yellow thick cheese-like material mixed with gray white hair (a). Sectioning of pedunculated nodules (diameter of 0.5 cm) found to have multiple components including skin and respiratory epithelium, which is consistent with a mature cystic teratoma/dermoid cyst (b); well-circumscribed tumor lesions noted with small, normochromatic, uniform tumor cells with an active nucleus (c). The tumor cells were positive for neuroendocrine tumor markers ((d) pancytokeratin stain and (e) chromogranin stain).

(a)

(b)

(c)

(d)

(e)