Collecting Duct Carcinoma of the Native Kidney in a Renal Transplant Recipient

Figure 2

Histologic and immunophenotypic features of collecting duct carcinoma. (a) Tumor cells form solid sheets (20x). (b) Linear and single cell infiltration (20x). (c) Prominent large nucleoli (40x). (d) Positive for PAX8, consistent with renal origin. (e) Negative for GATA-3, ruled out urothelial origin. (f) INI-1 retained, ruled out medullary carcinoma.

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