Case Report

An Atypical Case of Shiga Toxin Producing-Escherichia Coli Hemolytic and Uremic Syndrome (STEC-HUS) in a Lung Transplant Recipient

Table 1

TMA workup and results.

ExamsResults

Immunology
 Complement
  C3, mg/L (N: 880-1650)780
  C4, mg/L (N: 100-380)107
  CH50, % (N: 86-126)164
  Factor H, % (N: 70-130)61
  Antifactor H antibodies, UI (N: 0-300)< 5
  Factor I, % (N: 70-130)97
 ADAMTS13
  Activity, % (N: 40-130)22
  Anti-ADAMTS-13 antibodies, UI (N < 15)< 1.0
 Antineutrophil Cytoplasmic Antibodies (N < 20)< 20
 Antinuclear Antibodies (N < 160)< 160
 Antiphospholipid Antibody Syndrome
  Anticardiolipin antibodiesnegative
  Anti-β2GP1 antibodiesnegative

Infectiology
 PCR Shiga toxin (rectum biopsy)positive
 PCR Cytomegalovirus (blood and CSF)negative
 PCR Epstein-Barr Virus (blood, in log cop/mL)2.8
 HIV, HBV, HCV, HEV, Yersinia, Leptospira, Syphilis, Coxiella, Lyme serologiesnegative

TMA, thrombotic microangiopathy; CSF: cerebrospinal fluid; PCR: polymerase chain reaction.