Primary Hyperaldosteronism: A Rare Cause of Malignant Hypertension with Thrombotic Microangiopathy in a Kidney Transplant Recipient

Table 1

Thrombotic microangiopathy workup.

Workup	Result (normal range)
INR	1.0 (0.8-1.1)
aPTT	33.8 seconds (23-38)
Fibrinogen	5.66 g/L (1.5-4.0)
ADAMTS13 activity	67% (50-160)
Shiga toxin	Negative
C3	136 mg/dL (80-178)
C4	31.6 mg/dL (12-42)
Functional complement studies	Normal
Genetic complement studies	Normal
Antinuclear antibodies	Negative
Anti-dsDNA antibodies	Negative
Antiphospholipid antibodies	Negative
Extractable nuclear antigen antibodies	Negative
Serum protein electrophoresis	Normal
Vitamin B12	234 pmol/L (141-489)
Homocysteine	13.3 μgmol/L (<15)
Serum CMV viral load	Negative
Serum and urinary BK and JC viral load	Negative
Serum parvovirus B19 viral load	Negative
Anti-HIV 1 and 2 antibodies	Negative
Anti-HCV antibodies	Negative
HBs antigen and anti-HBc antibodies	Negative
Class I HLA antibodies	Negative
Class II HLA antibodies	Positive for 5 specificities, nondonor specific, maximum 15.600 MFI