Case Series

Effectiveness of Steroid Pulse Therapy for Systemic Side Effects after Bacillus Calmette-Guérin Intravesical Instillation Therapy: A Series of Five Cases

Table 1

Types of Bacillus Calmette-Guérin infections and treatments.

Type of BCG infectionTreatment

LocalInfection of the bladder, kidney, renal pelvis, ureter, prostate, and epididymis.Discontinue BCG. Administer isoniazid, rifampicin, and ethambutol for 3–6 months.
SystemicHematogenous dissemination of BCG to the systemic organs (BCG sepsis, hepatitis, and cerebromeningitis, among others).Discontinue BCG. Administer isoniazid, rifampicin, and ethambutol for six months.
EctopicEctopic infection of aneurysms and artificial organs (artificial joints, etc.), among others.Administer isoniazid and rifampicin for one year. Consider excision of the infected area.

BCG = Bacillus Calmette-Guérin.