Preliminary Evidence of Reduced Urge to Cough and Cough Response in Four Individuals following Remote Traumatic Brain Injury with Tracheostomy

Table 2

Average (SD) subjective UTC ratings (where 1 = no urge to cough and 10 = maximum urge to cough) and total cough count (CTot) at various concentrations of capsaicin in solution obtained from healthy controls (HCs) and participants with TBI.

	Capsaicin concentration (M)
	0	50	100	200	500
UTC (HC)	1.09 (0.31)	2.97 (1.11)	4.12 (1.50)	5.85 (1.85)	N/A
UTC (TBI)	1.25 (0.50)	2.88 (0.98)	3.25 (1.22)	4.50 (1.68)	4.79 (0.85)
CTot (HC)	0.00 (0.00)	3.06 (2.31)	4.81 (3.12)	6.19 (3.58)	N/A
CTot (TBI)	0.25 (0.5)	1.13 (0.37)	1.88 (1.07)	2.83 (0.43)	3.33 (0.72)

500 M capsaicin solution not administered to HC participants.