Research Article

EZH2 Inhibition Ameliorates Transverse Aortic Constriction-Induced Pulmonary Arterial Hypertension in Mice

Figure 4

EZH2 regulates TAC-induced PAH by targeting SOD1. Expression levels of SOD1 and EZH2 were measured by (a) Western blot and (b) qPCR (n = 5 for each group, versus sham control, ## versus TAC DMSO). (c) ChIP assays were performed with anti-EZH2 and anti-H3K27Me3 using lung tissues in indicated mice (n = 5 for each group, versus sham control, ##, # versus TAC DMSO).
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