Research Article

Lung Function and Relevant Clinical Factors in Very Low Birth Weight Preterm Infants with Chronic Lung Disease: An Observational Study

Table 1

Comparison of clinical variables between groups.

CLD (n = 27)No CLD (n = 18) value

Gestational age (weeks)27.19 ± 1.9829.61 ± 2.330.001
Birth weight (kg)0.92 ± 0.211.24 ± 0.16<0.001
Total days of respiratory support (days)72.15 ± 21.7929.61 ± 16.82<0.001
Duration of intubation (days)22.69 ± 26.82.17 ± 4.710.003
Male, n (%)15 (55.6)10 (55.6)1
Prenatal steroid use, n (%)12 (44.4)6 (33.3)0.543
RDS grade ≥3, n (%)13 (48.1)6 (33.3)0.371
PDA, n (%)20 (74.1)5 (27.8)0.005
Exogenous surfactant use, n (%)10 (37)2 (11.1)0.086
Exogenous surfactant use ≥2 times, n (%)5 (18.5)1 (5.6)0.377
Aminophylline use, n (%)24 (88.9)11 (61.1)0.064

All continuous data are presented as mean ± SD. RDS: respiratory distress syndrome; PDA: patent ductus arteriosus.