Canadian Respiratory Journal

Research Article

The Value of Combined Radial Endobronchial Ultrasound-Guided Transbronchial Lung Biopsy and Metagenomic Next-Generation Sequencing for Peripheral Pulmonary Infectious Lesions

Table 3

The most commonly identified pathogens by mNGS in 121 patients.


mNGS results	Immunocompromised (n = 70)	Nonimmunocompromised (n = 51)

Bacteria	Pseudomonas aeruginosa 9 (12.9)	Pseudomonas aeruginosa 4 (7.8)
	Klebsiella pneumoniae 7 (10.0)	Klebsiella pneumoniae 3 (5.9)
	Acinetobacter baumannii 6 (8.6)	Acinetobacter baumannii 3 (5.9)
	MTBC 6 (8.6)	MTBC 8 (15.7)

Viruses	EBV 11 (15.7)	EBV 4 (7.8)
	CMV 8 (11.4)	CMV 4 (7.8)
	Circovirus 5 (7.1)	Circovirus 3 (5.9)

Fungus	Aspergillus 11 (15.7)	Aspergillus 4 (7.8)
	Pneumocystis carinii 7 (10.0)	Pneumocystis carinii 3 (5.8)
	Rhizopus carinii 4 (5.7)	Actinomyces 2 (3.9)

Atypical pathogen	Mycoplasma 4 (5.7)	Mycoplasma 2 (3.9)
	Chlamydia 2 (2.9)	Chlamydia 1 (2.0)
		Legionellal 1 (2.0)

mNGS, metagenomic next-generation sequencing. MTBC, mycobacterium tuberculosis complex. EBV, Epstein–Barr virus. CMV, cytomegalovirus. Data are presented as no. (%) unless otherwise indicated.