Genetic Evolution of Mycobacterium abscessus Conferring Clarithromycin Resistance during Long-Term Antibiotic Therapy

Figure 3

Mutation profiles of clarithromycin-acquired resistant M. abscessus. We showed mutations present in 3 clarithromycin-acquired resistant M. abscessus strains compared to the initially clarithromycin-susceptible strains. Variants in red indicate that the variants exist in G179 compared with G142; variants in black indicate that the variants exist in A243 compared with A38; variants in blue indicate that the variants exist in A137 compared with G139. ATCC 19977 served as the reference genome.