Research Article

Relationship between Driving Pressure and Mortality in Ventilated Patients with Heart Failure: A Cohort Study

Table 2

Multivariable logistic regression analyses of driving pressure and in-hospital mortality.

VariableCrude model, n = 632P valueMinimally adjusted model, n = 632P valueFully adjusted model, n = 603P value

Driving pressure (cmH2O)1.07 (1.02, 1.11)0.00221.09 (1.04, 1.14)0.00021.12 (1.06, 1.18)<0.001

Driving pressure tertials
LowReferenceReferenceReference
Mid0.72 (0.46, 1.12)0.14300.71 (0.45, 1.12)0.13760.74 (0.44, 1.23)0.242
High1.65 (1.09, 2.49)0.01741.89 (1.23, 2.90)0.00392.26 (1.36, 3.77)0.002
P for trend0.0090.00190.002

Crude model: no other covariates were adjusted. Minimally adjusted model: we adjusted age and sex. Fully adjusted model: we adjusted age, sex, BMI, heart rate, MAP, WBC, hemoglobin, creatinine, CVP, NT-proBNP, PEEP, PH, PaO2, PaCO2, PF ratio, ventilation mode (CMV), VT/PBW, Elixhauser score, SOFA score, and SAPS score.