Relationship between Poorly Controlled Asthma and Sleep-Related Breathing Disorders in Children with Asthma: A Two-Center Study

Table 3

Risk factors for SRBD in asthmatic children.

Characteristic	Univariate analysis		Multivariate analysis
	OR (95% CI)	values	OR (95% CI)	values
Age in years	1.000 (0.905–1.105)	1.000
Obesity
No	1	0.023	1.995 (0.658–6.050)	0.223
Yes	3.111 (1.176–8.292)
Asthma
Well-controlled	1		1
Partly or uncontrolled	3.207 (1.617–6.360)	0.001	2.746 (1.215–6.209)	0.015
History of AR
No	1
Yes	1.740 (0.779–3885)	0.177
AR control status		0.004		0.005
Controlled	1		1
Uncontrolled	3.225 (1.441–7.220)		3.284 (1.430–7.544)
Allergy		0.251
No	1
Yes	2.412 (0.536–10.861)
ICS therapy		0.730
No	1
Yes	1.200 (0.427–3.373)
Nasal steroids therapy		0.696
No	1
Yes	1.417 (0.247–8.133)
Montelukast therapy		0.391
No	1
Yes	1.475 (0.607–3.586)
Antihistamines therapy		0.780
No	1
Yes	1.105 (0.549–2.223)

The data from multivariate analysis were after adjusting for obesity, asthma control status, and AR control status.  < 0.05 was considered a statistically significant difference. CI, confidence interval; OR, odds ratios; AR, allergic rhinitis; ICS, inhaled corticosteroid. The variables with statistical differences are indicated in bold.