Diagnostic Value of Fractional Exhaled Nitric Oxide and Small Airway Function in Differentiating Cough-Variant Asthma from Typical Asthma

Table 3

Correlations between FeNO or small airways function and other parameters.

	Single correlation		Multiple regression analysis
a. FeNO
TA	r	P	B	P
Male/female	−0.132	0.186	−0.204	0.099
Age	−0.016	0.877	0.001	0.992
BMI	−0.051	0.611	0.045	0.704
FEV1/FVC	−0.140	0.159	0.047	0.694
PEF	−0.005	0.96	−0.096	0.433
PD20 (µmoL)	−0.023	0.817	−0.096	0.384
DLCO	0.014	0.890	−0.095	0.395
RV/TLC	−0.030	0.763	0.079	0.483
CVA	r	P	B	P
Male/female	−0.131	0.186	−0.170	0.108
Age	0.044	0.656	−0.139	0.219
BMI	−0.080	0.422	−0.197	0.055
FEV1/FVC	−0.153	0.122	−0.067	0.586
PEF	−0.047	0.634	0.021	0.861
PD20 (µmoL)	0.003	0.976	−0.012	0.906
DLCO	0.082	0.410	−0.022	0.834
RV/TLC	0.129	0.191	0.159	0.140
b. MMEF75%/25%
TA	r	P	B	P
Male/female	−0.158	0.112	−0.199	0.005
Age	−0.232	0.019	−0.078	0.216
BMI	0.050	0.615	−0.226	0.001
FEV1/FVC	0.699	<0.001	0.635	<0.001
PEF	0.500	<0.001	0.157	0.025
PD20 (µmoL)	0.093	0.351	-0.025	0.683
DLCO	0.264	0.007	0.200	0.002
RV/TLC	−0.375	<0.001	0.231	<0.001
FeNO	−0.075	0.454	−0.113	0.053
CVA	r	P	B	P
Male/female	−0.107	0.278	−0.173	<0.001
Age	−0.278	0.004	0.051	0.203
BMI	0.048	0.630	0.008	0.825
FEV1/FVC	0.905	<0.001	0.881	<0.001
PEF	0.431	<0.001	0.105	0.015
PD20 (µmoL)	0.197	0.045	0.025	0.493
DLCO	0.263	0.007	0.019	0.613
RV/TLC	−0.209	0.034	−0.092	0.017
FeNO	−0.082	0.409	0.029	0.427
c. FEF50%
TA	r	P	B	P
Male/female	−0.099	0.323	−0.174	0.006
Age	−0.268	0.006	−0.090	0.114
BMI	0.053	0.599	−0.227	<0.001
FEV1/FVC	0.810	<0.001	0.717	<0.001
PEF	0.532	<0.001	0.120	0.058
PD20 (µmoL)	0.100	0.318	0.012	0.831
DLCO	0.207	0.037	0.179	0.002
RV/TLC	−0.351	<0.001	−0.205	0.001
FeNO	−0.101	0.314	−0.084	0.114
CVA	r	P	B	P
Male/female	−0.057	0.564	−0.096	0.068
Age	−0.229	0.019	0.088	0.114
BMI	0.066	0.503	0.036	0.469
FEV1/FVC	0.861	<0.001	0.828	<0.001
PEF	0.460	<0.001	0.101	0.091
PD20 (µmoL)	0.208	0.034	0.021	0.675
DLCO	0.202	0.039	0.008	0.876
RV/TLC	−0.229	0.019	−0.158	0.003
FeNO	−0.127	0.200	0.007	0.887
d. FEF25%
TA	r	P	B	P
Male/female	−0.157	0.115	−0.273	0.003
Age	−0.133	0.182	−0.101	0.221
BMI	−0.054	0.588	−0.363	<0.001
FEV1/FVC	0.437	<0.001	0.467	<0.001
PEF	0.352	<0.001	0.107	0.239
PD20 (µmoL)	−0.051	0.609	−0.121	0.139
DLCO	0.314	0.001	0.232	0.006
RV/TLC	−0.307	0.002	−0.194	0.020
FeNO	−0.048	0.631	−0.150	0.051
CVA	r	P	B	P
Male/female	−0.125	0.207	−0.233	<0.001
Age	−0.401	<0.001	0.010	0.836
BMI	−0.009	0.926	−0.087	0.052
FEV1/FVC	0.900	<0.001	0.888	<0.001
PEF	0.262	0.007	−0.003	0.950
PD20 (µmoL)	0.198	0.044	0.030	0.504
DLCO	0.288	0.003	0.033	0.465
RV/TLC	−0.116	0.240	0.031	0.510
FeNO	−0.080	0.422	0.038	0.390

; ; .