Polygonatum Polysaccharide Regulates Macrophage Polarization and Improves LPS-Induced Acute Lung Injury through TLR4-MAPK/NF-<i>κ</i>B Pathway

<div>Effects of PSPs on M1 and M2 phenotypic polarization and TLR4-MAPK/NF-<i>κ</i>B signaling pathway of mouse macrophages. (a) The effect of PSPs on M1 and M2 phenotypic polarization of mouse macrophages was measured by flow cytometry. (b) The expression of TLR4-MAPK/NF-<i>κ</i>B signal proteins in lung tissue. 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27V0H384Z"></path></g></svg>;</span> compared with LPS group, <span class="nowrap"><svg height="12.1645pt" id="M65" style="vertical-align:-0.6370001pt" version="1.1" viewbox="-0.0498162 -11.5275 54.2341 12.1645" width="54.2341pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.741)"><path d="M457 455H370L403 612H360L326 455H218L252 612H210L175 455H77L68 394H161L132 257H31L20 196H117L77 19H120L159 196H268L230 19H272L311 196H402L412 257H325L355 394H447L457 455ZM313 394L283 257H175L204 394H313Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,4.432,-5.741)"><path d="M457 455H370L403 612H360L326 455H218L252 612H210L175 455H77L68 394H161L132 257H31L20 196H117L77 19H120L159 196H268L230 19H272L311 196H402L412 257H325L355 394H447L457 455ZM313 394L283 257H175L204 394H313Z"></path></g><g transform="matrix(.013,0,0,-0.013,9.395,0)"><path d="M600 480C600 590 528 650 384 650H143L137 622C222 614 225 607 210 531L130 127C113 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Canadian Respiratory Journal

fig11

Figure 11

Figure 11: Polygonatum Polysaccharide Regulates Macrophage Polarization and Improves LPS-Induced Acute Lung Injury through TLR4-MAPK/NF-<i>κ</i>B Pathway 

Canadian Respiratory Journal

Polygonatum Polysaccharide Regulates Macrophage Polarization and Improves LPS-Induced Acute Lung Injury through TLR4-MAPK/NF-κB Pathway

Figure 11