Research Article

The Efficacy and Cost-Effectiveness of Umeclidinium/Vilanterol versus Tiotropium in Symptomatic Patients with Chronic Obstructive Pulmonary Disease

Table 4

Treatment-related costs of chronic obstructive pulmonary disease.

Input parameterValueSource/assumption

Drug costsQuarterly prescription costs (calculated based on the winning bid price in 2020)
 UMEC/VI$95.22http://www.yaozh.com
 TIO$180.53http://www.yaozh.com

Other medical costsQuarterly costs
 Moderate COPD$143.37Reference [14]
 Severe COPD$204.29
 Very severe COPD$319.45Physician visit: local charge

Adverse events (AEs)Costs a (per reported AE)Physician visit and local processing charge
 Back pain$3.19Physician visit: local charge
 Cough$32.2Physician visit: local charge
 Headache$3.19Physician visit and local processing charge
 Nasopharyngitis$3.19
 Upper respiratory tract infection$39.21

Exacerbation cost
 Severe exacerbation$2,129.690
 Nonsevere exacerbation$44.824