Research Article
Characteristics and Prognostic Nomogram for Primary Lung Lepidic Adenocarcinoma
Table 1
Characteristics of patients with LPA compared with lung ADC-NOS.
| | Characteristics | LPA n = 4191 (%) | ADC-NOS n = 95004 (%) | value |
| | Age, years | | 0–69 | 1994 (47.6) | 55203 (58.1) | <0.001 | | 70–79 | 1438 (34.3) | 26630 (28.0) | | | ≥80 | 759 (18.1) | 13171 (13.9) | | | Sex | | Male | 1591 (38.0) | 46856 (49.3) | <0.001 | | Female | 2600 (62.0) | 48148 (50.7) | | | Race | | White | 3372 (80.5) | 74655 (78.6) | <0.001 | | Black | 356 (8.5) | 11469 (12.1) | | | Others | 463 (11.0) | 8880 (9.3) | | | Marital status | | Married | 2460 (58.7) | 52085 (54.8) | <0.001 | | Single | 1731 (41.3) | 42919 (45.2) | | | Education | | High | 2065 (49.3) | 47790 (50.3) | 0.197 | | Low | 2126 (50.7) | 47214 (49.7) | | | Income | | High | 2055 (49.0) | 48741 (51.3) | 0.004 | | Low | 2136 (51.0) | 46263 (48.7) | | | Laterality | | Left | 1620 (38.7) | 36177 (38.1) | <0.001 | | Right | 2447 (58.4) | 54374 (57.2) | | | Unknown | 124 (3.0) | 4453 (4.7) | | | Lobe | | Upper | 2195 (52.4) | 51289 (54.0) | <0.001 | | Middle | 199 (4.7) | 4317 (4.5) | | | Lower | 1444 (34.5) | 24035 (25.3) | | | Unknown | 353 (8.4) | 15363 (16.2) | | | Tumor size | | <3 cm | 2229 (53.2) | 31494 (33.2) | <0.001 | | ≥3 and <5 cm | 915 (21.8) | 24387 (25.7) | | | ≥5 cm | 530 (12.6) | 22377 (23.6) | | | Unknown | 517 (12.3) | 16746 (17.6) | | | Separate tumor nodules | | Yes | 361 (8.6) | 15476 (16.3) | <0.001 | | No | 1195 (28.5) | 40383 (42.5) | | | Unknown | 2635 (62.9) | 39145 (41.2) | | | Pleural invasion | | Yes | 117 (2.8) | 5017 (5.3) | <0.001 | | No | 714 (17.0) | 11117 (11.7) | | | Unknown | 3360 (80.2) | 78870 (83.0) | | | Grade | | I | 1636 (39.0) | 6203 (6.5) | <0.001 | | II | 1086 (25.9) | 20984 (22.1) | | | III | 249 (5.9) | 27993 (29.5) | | | IV | 7 (0.2) | 606 (0.6) | | | Unknown | 1213 (28.9) | 39218 (41.3) | | | Stage | | I | 2261 (53.9) | 19370 (20.4) | <0.001 | | II | 172 (4.1) | 4007 (4.2) | | | III | 603 (14.4) | 20127 (21.2) | | | IV | 1155 (27.6) | 51500 (54.2) | | | Primary tumor surgery | | Yes | 2646 (63.1) | 24886 (26.2) | <0.001 | | No/unknown | 1545 (36.9) | 70118 (73.8) | | | Metastatic tumor surgery | | Yes | 74 (1.8) | 5499 (5.8) | <0.001 | | No/unknown | 4117 (98.2) | 89505 (94.2) | | | Radiotherapy | | Yes | 639 (15.2) | 39072 (41.1) | <0.001 | | No/unknown | 3552 (84.8) | 55932 (58.9) | | | Chemotherapy | | Yes | 1226 (29.3) | 46273 (48.7) | <0.001 | | No/unknown | 2965 (70.7) | 48731 (51.3) | |
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ADC: adenocarcinoma; LPA: lepidic adenocarcinoma; NOS: not otherwise specified.
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