Small Airway Dysfunction in Chronic Bronchitis with Preserved Pulmonary Function
Table 1
Baseline characteristics of patients in this study (Mean ± SD).
Variables
Control (n = 77)
PRISm (n = 80)
COPD (Gold 1, 2) (n = 186)
P value
Age (y)
67.42 ± 9.72
70.68 ± 10.8
68.17 ± 10.85
0.116
Sex (F/M)
20/57
19/61
26/160
BMI (kg/m2)
24.03 ± 2.98
24.02 ± 4.03
23.77 ± 3.53
0.797
Smoking (pack-year)
31.86 ± 21.66
31.27 ± 18.18
41.9 ± 25.64
0.007
CAT
15.45 ± 8.82
16.25 ± 9.12
18.53 ± 8.25
0.014
mMRC
0.96 ± 0.98
1.43 ± 1.13
1.26 ± 1.1
0.024
WBC (×109/L)
6.29 ± 2.33
6.38 ± 1.94
7.26 ± 3.28
0.011
N (%)
64.31 ± 11.10
65.47 ± 11.67
68.61 ± 11.41
0.010
E (%)
2.62 ± 2.27
3.08 ± 3.39
2.69 ± 2.7
0.504
BMI = body mass index, CAT = COPD Assessment Test score, mMRC = Modified British Medical Research Council, WBC = white blood cell count, N = neutrophil count, E = eosinophils count. , , versus Control, , , versus COPD.
