Small Airway Dysfunction in Chronic Bronchitis with Preserved Pulmonary Function
Table 2
Analysis of variances results for three groups in this study (mean ± SD).
Control (n = 77)
PRISm (n = 80)
COPD (n = 186)
P value
FEV1% pred
93 ± 10.71
63.96 ± 12.64
63.95 ± 11.44
<0.001
FVC% pred
92.26 ± 11.88
63.82 ± 13.53,
84.1 ± 13.92
<0.001
FEV1/FVC (%)
79.52 ± 6.54
78.46 ± 6.39
58.77 ± 7.12
<0.001
FEV1/FEV6 (%)
74.35 ± 10.32
72.75 ± 9.02
58.89 ± 7.46
<0.001
MEF25% pred
70.43 ± 31.87
47.07 ± 22.48,
31.04 ± 11.30
<0.001
MEF50% pred
75.13 ± 26.12
45.17 ± 15.88,
27.70 ± 8.66
<0.001
MMEF25–75% pred
73.46 ± 23.28
45.59 ± 15.01,
28.73 ± 8.64
<0.001
RV/TLC (%)
45.03 ± 7.05
53.92 ± 9.98
51.99 ± 9.45
<0.001
R5 (kPa s L−1)
0.41 ± 0.11
0.45 ± 0.11
0.48 ± 0.14
<0.001
R20 (kPa s L−1)
0.34 ± 0.08
0.34 ± 0.07
0.34 ± 0.07
0.93
R5–R20 (kPa s L−1)
0.07 ± 0.05
0.11 ± 0.07,
0.14 ± 0.09
<0.001
X5 (kPa s L−1)
−0.11 ± 0.05
−0.16 ± 0.08,
−0.19 ± 0.12
<0.001
Fres (1/s)
15.48 ± 5.41
18.04 ± 3.60,
19.85 ± 4.62
<0.001
Ax (kPa/L)
0.54 ± 0.49
0.97 ± 0.71,
1.46 ± 1.12
<0.001
, , versus control, , , versus COPD, The number of patients for this parameter is control (n = 36), PRISm (n = 36), and COPD (n = 147) due to incomplete data of FEV6.
