Mortality Predictive Value of APACHE II and SOFA Scores in COVID-19 Patients in the Intensive Care Unit

Table 2

Odds ratio and 95% confidence intervals of APACHE II and mean SOFA scores and comorbidities of patients hospitalized for COVID-19 at intensive care unit.

Variable	Crude OR	value	Adjusted OR	value
APACHE II score	1.17 (1.1–1.2)	≤0.001	1.21 (1.13–1.30)	≤0.001
APACHE II group
<13	Reference		Reference
≥13	9.6 (4.9–18.9)	≤0.001	10.7 (5.0–22.9)	≤0.001
Mean SOFA score	2.7 (2.07–3.61)	≤0.001	2.83 (2.09–3.83)	≤0.001
Mean SOFA group
<5	Reference		Reference
≥5	33.7 (15.2–74.6)	≤0.001	32.4 (14.4–72.9)	≤0.001
Comorbidities
No	Reference		Reference
Any	2.7 (1.4–5.3)	0.004	2.1 (0.78–5.66)	0.14
Kidney diseases	4.23 (0.90–19.82)	0.067	7.12 (1.36–37.4)	0.020
Cardiovascular	0.87 (0.47–1.61)	0.66	0.71 (0.33–1.52)	0.384
Respiratory	4.73 (1.33–16.80)	0.016	8.56 (1.98–37.04)	0.004
Malignancy	2.52 (1.02–6.27)	0.04	4.35 (1.51–12.57)	0.007
Diabetes mellitus	1.07 (0.61–1.89)	0.80	1.61 (0.83–3.15	0.15
Hypertension	0.59 (0.34–1.05)	0.072	0.59 (0.29–1.25)	0.16

OR: odds ratio, APACHE II: acute physiology and chronic health evaluation, and SOFA: sequential organ failure assessment.