Canadian Respiratory Journal

Research Article

Mortality Predictive Value of APACHE II and SOFA Scores in COVID-19 Patients in the Intensive Care Unit

Table 4

Comparison of laboratory findings between survived and nonsurvived patients.


Variable	Survived mean ± SD	Nonsurvived mean ± SD	value	95% CI
Variable	Survived mean ± SD	Nonsurvived mean ± SD	value	Lower	Upper

WBC	8971.3 ± 4564.6	12091.1 ± 5240.9	≤0.001	−4497.313	−1742.337
Neutrophil	78.4 ± 6.9	86.6 ± 7.6	≤0.001	−10.256	−6.276
Lymphocyte	15.7 ± 6.5	9 ± 5.5	≤0.001	5	8.329
Platelet	303261.3 ± 128630.4	232488 ± 117520.3	≤0.001	36702.921	104843.534
Hb	12.2 ± 1.7	11.6 ± 1.8	0.013	0.132	1.143
ESR	78.34 ± 23.8	76.50 ± 29.6	0.703	−7.674	11.336
CRP	77.1 ± 52.9	149.2 ± 86.1	≤0.001	−94.866	−49.363
Lactate	34.82 ± 9.7	34.50 ± 15.8	0.963	−14.115	14.764
BS	141.19 ± 44.2	176.78 ± 73.5	≤0.001	−53.676	−17.495
Urea	46.65 ± 24.9	81.11 ± 41.2	≤0.001	−44.244	−24.682
Creatinine	1.12 ± 0.7	1.65 ± 0.9	≤0.001	−0.765	−0.293
ALT	49.68 ± 33.4	95.49 ± 182.9	0.030	−87.026	−4.594
AST	44.94 ± 34.4	124.26 ± 354.1	0.045	−56.797	−1.832
Alk-P	200.61 ± 113.9	280.17 ± 229.9	0.006	−136.228	−22.893
Bili-T	1.46 ± 0.9	2.35 ± 2.2	0.002	−1.456	−0.332
Bili-D	0.40 ± 0.2	1.03 ± 1.3	≤0.001	−0.923	−0.336
Albumin	3.21 ± 0.3	2.70 ± 0.5	≤0.001	0.285	0.717
LDH	593.52 ± 159.4	865.03 ± 377.2	≤0.001	−382.606	−160.398
CPK	311.41 ± 1104.9	250.64 ± 292.4	0.702	−253.617	375.155
Pro-BNP	1577.18 ± 2670.3	1828.57 ± 1827.01	0.654	−1365.158	862.373
D-dimer	1797.69 ± 1222.7	4697.44 ± 5945.9	0.004	−4846.196	−953.316
Ca	8.15 ± 0.3	7.87 ± 0.5	≤0.001	0.166	0.453
PCT	2.38 ± 3.5	7.26 ± 19.7	0.266	−13.565	3.816
pH	7.42 ± 0.04	7.38 ± 0.1	≤0.001	0.022	0.059
PO₂	73.52 ± 16.7	79.78 ± 26.3	0.120	−14.165	1.654
PCO₂	37.2 ± 5.5	40.1 ± 10.1	0.021	−5.106	−0.426
HCO₃	24.31 ± 3.6	23.76 ± 4.8	0.369	−0.657	1.757
BE	1.05 ± 3.5	−1.02 ± 4.5	≤0.001	0.946	3.226
FiO₂	61.1 ± 10.7	80.6 ± 15.1	≤0.001	−23.335	−15.594
SPO₂	92.8 ± 2.1	89.7 ± 6.3	≤0.001	1.727	4.454

Variables are the mean value duration of admission days. WBC: white blood cells, Hb: hemoglobin, ESR: erythrocyte sedimentation rate, CRP: C-reactive protein, BS: blood sugar, ALT: Alanine aminotransferase test, AST: aspartate aminotransferase test, Alk-P: alkaline phosphate, Bili-T: total bilirubin, Bili-D: direct bilirubin, LDH: lactic acid dehydrogenase, CPK: creatine phosphokinase, Pro-BNP: pro-brain natriuretic peptide, Ca: calcium, PCT: procalcitonin, PO₂: partial pressure of oxygen, PCO₂: partial pressure of carbon dioxide, BE: base excess, FiO₂: fraction of inspired oxygen, and SPO₂, peripheral capillary oxygen saturation.