SR9009 Regulates Acute Lung Injury in Mice Induced by Sepsis

Figure 1

ELISA detection of proinflammatory cytokine production: (a) IL-6, (b) TNF-α, and (c) anti-inflammatory cytokine production IL-10 in RAW246.7 cells after treatment with DMSO (control group), LPS, SR9009, and SR9009 + LPS, respectively. Normalized mRNA expressions of (d) IL-6, (e) TNF-α, and (f) IL-10 in RAW246.7 cells after treatment with DMSO (control group), LPS, SR9009, and SR9009 + LPS, respectively. (g) Mean fluorescence intensity of CD86 and CD206 in RAW246.7 before and after Rev-erbα regulation. Significant differences: , , , and .

(a)

(b)

(c)

(d)

(e)

(f)

(g)