Comparison of CRP, Procalcitonin, Neutrophil Counts, Eosinophil Counts, sTREM-1, and OPN between Pneumonic and Nonpneumonic Exacerbations in COPD Patients

Table 2

Clinical parameters and biomarker differences evaluated at admission.

	AECOPD patients	CAP + AECOPD patients
No.	93	52
Fever, n (%)	2 (2.2)	5 (9.6)	0.11
Increased sputum volume, n (%)	73 (78.5)	48 (92.3)	0.03
Aggravating cough, n (%)	89 (95.7)	50 (96.2)	1.0
Increased sputum purulence, n (%)	32 (34.4)	30 (57.7)	0.007
Pleuritic pain, n (%)	8 (8.6)	7 (13.5)	0.36
Dyspnea, n (%)	83 (89.2)	50 (96.2)	0.26
Intensive care unit admission, n (%)	2 (2.2)	2 (3.8)	0.95
Hospital stay, median (IQR)	8.0 (7.0–11.5)	10.0 (8.0–14.0)	0.03
Noninvasive mechanical ventilation, n (%)	2 (2.2)	3 (5.8)	0.50
Invasive mechanical ventilation, n (%)	0 (0)	0 (0)	-
Emergency treatment, n (%)	0 (0)	2 (3.8)	0.13
CRP, mg/dL	5.86 (3.27–18.7)	51.3 (16.6–102.7)	<0.001
PCT, ng/mL	0.049 (0.03–0.07)	0.09 (0.04–0.18)	<0.001
Neu (10^9/L)	4.68 (4.05–6.55)	6.78 (4.22–9.69)	0.01
EOS (10^9/L)	0.14 (0.02–0.35)	0.1 (0.02–0.19)	0.09
sTREM-1, pg/mL	115.3 (66–241.65)	104.3 (64.12–193.7)	0.47
OPN, ng/mL	12.61 (7.37–28.2)	20.6 (11.8–49.0)	0.015