Research Article

Association of GSTM1 and GSTT1 Null Genotypes with Toluene Diisocyanate-Induced Asthma

Table 2

Comparison of GSTM1 and GSTT1 genotype frequencies according to the response of the TDI challenge.

GenotypeTDI-PA (%)/TDI-NA (%)OR (95% CI) value

GSTM1
Wild6 (22.2)/13 (50.0)1.0 (reference)0.035
Null21 (77.8)/13 (50.0)3.50 (1.06–11.49)

GSTT1
Wild11 (40.7)/15 (57.7)1.0 (reference)0.217
Null16 (59.3)/11 (42.3)1.98 (0.66–5.91)

TDI-PA: TDI challenge positive asthma and TDI-NA: TDI challenge negative asthma. values were obtained using logistic regression analysis and were considered significant when less than 0.05.