Risk Factors Associated with Impairment in Pulmonary Diffusing Capacity among Patients with Noncystic Fibrosis Bronchiectasis
Table 2
Multivariate analysis of risk factors associated with impaired pulmonary diffusing capacity diagnosed by DLCO <80% prediction (a) and DLCO/VA <80% prediction (b), and decreased alveolar volume diagnosed by VA<80% prediction (c) among non-CF bronchiectasis patients.
Age (years)
(a) Multivariate analysis of impaired pulmonary diffusing capacity diagnosed by DLCO <80% prediction
Β-value
SE value
Wald value
OR value
95% CI
value
0.475
0.019
6.346
1.048
1.010∼1.087
0.0
Body mass index
<18.5
1.250
0.525
5.667
3.490
1.247∼9.766
0.017
≥24
−0.855
0.461
3.437
0.425
0.172∼1.050
0.064
18.5∼24
Chronic obstructive pulmonary disease
1.217
0.413
8.693
3.377
1.504∼7.582
0.003
18.31
2.959∼171.2
Interstitial lung disease
2.908
1.114
6.501
6
32
0.011
Modified Reiff score
0.202
0.057
12.577
1.224
1.094∼1.368
<0.001
(b) Multivariate analysis of impaired pulmonary diffusing capacity diagnosed by DLCO/VA <80% prediction
Β-value
SE value
Wald value
OR value
95% CI
value
Duration of disease (years)
0.061
0.020
9.866
1.063
1.023∼1.105
0.002
Frequency of exacerbation in the last 2 years
0.200
0.108
3.440
1.221
0.989–1.508
0.064
Hemoglobin (g/L)
−0.033
0.013
6.077
0.968
0.943∼0.993
0.014
3.178∼18.50
Chronic obstructive pulmonary disease
2.037
0.449
20.547
7.669
5
<0.001
(c) Multivariate analysis of decreased alveolar volume diagnosed by VA <80% prediction
