Research Article

Dexmedetomidine Attenuates LPS-Stimulated Alveolar Type II Cells’ Injury through Upregulation of miR-140-3p and Partial Suppression of PD-L1 Involving Inactivating JNK-Bnip3 Pathway

Figure 1

DEX protects alveolar epithelial cells from inflammation by promoting miR-140-3p level and suppressing PD-1/PD-L1 expression. (a) The survival rate of RLE-6TN cells induced by LPS and DEX. (b) The relative expression of miR-140-3p in RLE-6TN cells induced by LPS and DEX. The relative expression of PD-1/PD-L1 in RLE-6TN cells induced by LPS and DEX. Data are presented as means ± SD (n = 3; compared to control , compared to LPS-induced #).
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