ADAM33 Silencing Inhibits Vascular Smooth Muscle Cell Migration and Regulates Cytokine Secretion in Airway Vascular Remodeling via the PI3K/AKT/mTOR Pathway

Figure 3

Effect of ADAM33 silencing on the PI3K/AKT/mTOR and Rho/ROCK pathways. HASMCs were transfected with LV-ADAM33 or a negative control vector (LV-NC). The control group remained untreated. (a) The mRNA expression levels of PI3K, AKT, mTOR, Rho, and ROCK were detected by qRT-PCR. (b–i) The protein levels of PI3K, AKT, p-AKT, mTOR, p-mTOR, Rho, and ROCK were measured by Western blot assay; .

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