Research Article
ADAM33 Silencing Inhibits Vascular Smooth Muscle Cell Migration and Regulates Cytokine Secretion in Airway Vascular Remodeling via the PI3K/AKT/mTOR Pathway
Figure 4
Effect of ADAM33 knockout on the expression of FOXO1 and cyclin D1. HASMCs were transfected with LV-ADAM33 or a negative control vector (LV-NC). The control group remained untreated. (a, b) The mRNA expression levels of FOXO1 and cyclin D1 were detected by qRT-PCR. (c–f) The protein levels of FOXO1, p-FOXO1, and cyclin D1 were measured by Western blot assay; .
(a) |
(b) |
(c) |
(d) |
(e) |
(f) |