Comparative Study of Ectopic Lymphoid Aggregates in Sheep and Murine Models of Bleomycin-Induced Pulmonary Fibrosis

<div>Immunohistochemical staining of T lymphocytes (CD-3 +ve) in sheep and mouse lung tissues (a). Arrows indicate examples of T lymphocytes. The graph represents the T-cell infiltration levels between saline-infused and bleomycin-infused lung segments of sheep (<i>n</i> = 8) and lung tissues from saline control (<i>n</i> = 7) and bleomycin-treated mice (<i>n</i> = 7) (b). Twenty representative nonoverlapping fields in the lung parenchyma were captured under ×40 magnification for analysis. Each bar represents the mean ± standard error of the mean. 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Canadian Respiratory Journal

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Figure 5

Figure 5: Comparative Study of Ectopic Lymphoid Aggregates in Sheep and Murine Models of Bleomycin-Induced Pulmonary Fibrosis 