Research Article

The Effects of Nebulized Inhaled Triptolide on Airway Inflammation in a Mouse Model of Asthma

Table 3

Changes in mRNA transcription of three TFs and expression of CD17+ T lymphocytes.

BlkNSDexTPF

IL-17 (∆Ct)10.69 ± 0.296.19 ± 0.668.80 ± 0.418.06 ± 0.32105.95<0.001
RORγt (∆Ct)10.90 ± 0.415.32 ± 0.458.96 ± 0.657.43 ± 0.44143.33<0.001
FoxP3 (∆Ct)1.32 ± 0.184.48 ± 0.482.42 ± 0.283.07 ± 0.3688.32<0.001
CD4CD17 (%)1.18 ± 0.33 ^9.53 ± 2.74 ˜4.23 ± 2.26 ^   ˜6.76 ± 2.99 ^   ˜13.70<0.001

Between any two groups in pairwise comparison: ;  ^either group in pairwise comparison with NS group: ;  ˜either group in pairwise comparison with Blk group: .