Association of Upon-Diagnosis Blood Eosinophilic Count with Frequency and Severity of Annual Exacerbation in Chronic Obstructive Pulmonary Disease: A Prospective Longitudinal Analysis

Table 2

Association of an annual COPD exacerbation with the blood eosinophils level for patients with baseline serum eosinophil 200–1,200 cell per microliter using the linear regression model.

Model 1		Model 2
Beta (95% CI)	value	Beta (95% CI)	value
184 (156–285)	<0.001	179 (153–294)	0.008

Beta shows the number of eosinophilic counts (cell/microliter) increased by each annual exacerbation. Model 1: unadjusted. Model 2: further adjusted for COPD medications (bronchodilators, inhaler corticosteroids, domiciliary oxygen, and rehabilitation). COPD = chronic obstructive pulmonary disease.