Association of Upon-Diagnosis Blood Eosinophilic Count with Frequency and Severity of Annual Exacerbation in Chronic Obstructive Pulmonary Disease: A Prospective Longitudinal Analysis
Table 5
Clinical and laboratorial characteristics of the patients admitted in emergency department whilst exacerbation of COPD.
Variables
Eosinophilic n = 395
Noneosinophilic n = 578
values
Gasometrical
PaO2 (mmHg)
61.2 ± 18.2
59.9 ± 15.4
0.38
PaCO2 (mmHg)
39.2 ± 5.9
38.8 ± 5.6
0.23
pH
7.25 ± 2.6
7.30 ± 3.5
0.09
Oxygen saturation without oxygen support (%)
91.1 ± 3.6
92.6 ± 3.7
0.03
Laboratorial
CRP qualitative (0+ to 4+)
2 (2, 3)
1 (2, 2)
0.09
ESR (mg/L)
16 ± 5.6
15 ± 4.3
0.21
Leucocytes (cell per microliter)
6,850 (5,610, 8,560)
6,740 (5,590, 8,445)
0.09
Eosinophils (cell per microliter)
361 (210, 643)
176 (141, 352)
0.00
Clinical severity
Only bacterial pneumonia
81 (20.5)
98 (17.0)
0.16
Only viral pneumonia
39 (9.8)
50 (8.6)
0.52
Bacterial and viral pneumonia coinfection
24 (6.1)
18 (3.1)
0.02
ICU-admission (yes)
100 (25.3)
142 (24.5)
0.19
Invasive mechanical ventilation (yes)
27 (6.8)
30 (5.2)
0.25
Annual exacerbation event (yes)
101 (25.6)
88 (15.2)
0.01
Annual exacerbation frequency (number of events)
2.26 ± 1.3
1.23 ± 0.3
0.00
Interval for next exacerbation (days)
135.9 ± 25.9
197.0 ± 34.0
0.00
Duration of hospitalization per exacerbation (days)
