Impact of Moderate to Severe Renal Impairment on Mortality and Appropriate Shocks in Patients with Implantable Cardioverter Defibrillators

Table 4

Risk ratios and 95% confidence intervals for all-cause mortality based on serum creatinine.

Serum creatinine (mg/dL)	𝑛	Death (%)	Unadjusted	Adjusted*
1st quartile (<1.0)	108	7.41	ref	ref
2nd quartile (1.0–)	128	13.28	1.79 (0.81–3.99)	1.77 (0.80–3.94)
3rd quartile (1.2–)	110	20.00	2.70 (1.26–5.80)	2.72 (1.28–5.82)
4th quartile (1.4–)	136	32.35	4.37 (2.15–8.88)	3.73 (1.84–7.58)

*Adjusted for age (≥75 or <75 years), sex, indication for ICD implantation (primary, secondary), NYHA class, antiarrhythmics, ace inhibitor, digoxin, aldosterone blocker, and betablocker use and LVEF (<30%, ≥30%).