Review Article
Vascular Endothelial Growth Factor Inhibitor-Induced Hypertension: Basics for Primary Care Providers
Table 2
Common terminology criteria for adverse events v3.0 (CTCAE): hypertension adult.
| Grade | |
| 1 | Asymptomatic, transient (<24 hrs) increase by >20 mm Hg (diastolic) or to >150/100 if previously WNL; intervention not indicated |
| 2 | Recurrent or persistent (>24 hrs) or symptomatic increase by >20 mm Hg (diastolic) or to >150/100 if previously WNL; monotherapy may be indicated |
| 3 | Requiring more than one drug or more intensive therapy than before |
| 4 | Life-threatening consequences (e.g., hypertensive crisis) |
| 5 | Death |
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Abbreviations: WNL, within normal limits. Publication date: August 9, 2006. Available at: http://ctep.info.nih.gov/protocolDevelopment/electronic_applications/docs/ctcaev3.pdf.
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