Review Article

Vascular Endothelial Growth Factor Inhibitor-Induced Hypertension: Basics for Primary Care Providers

Table 2

Common terminology criteria for adverse events v3.0 (CTCAE): hypertension adult.

Grade

1Asymptomatic, transient (<24 hrs) increase by >20 mm Hg (diastolic) or to >150/100 if previously WNL; intervention not indicated

2Recurrent or persistent (>24 hrs) or symptomatic increase by >20 mm Hg (diastolic) or to >150/100 if previously WNL; monotherapy may be indicated

3Requiring more than one drug or more intensive therapy than before

4Life-threatening consequences (e.g., hypertensive crisis)

5Death

Abbreviations: WNL, within normal limits.
Publication date: August 9, 2006. Available at: http://ctep.info.nih.gov/protocolDevelopment/electronic_applications/docs/ctcaev3.pdf.