Efficacy of Wenxin Keli Plus Amiodarone versus Amiodarone Monotherapy in Treating Recent-Onset Atrial Fibrillation

Table 2

Clinical parameters, echocardiographic (ECHO), and ECG characteristics of patients after admission.

Variables	AMIO ()	AMIO + WXKL ()	value
ECHO
LAD (mm)	40.5 ± 5.9	40.9 ± 5.5	0.85
LVEDD (mm)	46.7 ± 4.0	48.4 ± 4.8	0.21
LVESD (mm)	30.0 ± 5.4	31.4 ± 6.3	0.44
IVS (mm)	9.8 ± 1.6	9.6 ± 2.5	0.75
LVEF (%)	58.1 ± 8.7	61.3 ± 7.3	0.22
ECG
QTc1 (ms)	437 ± 29	456 ± 25	0.03
QTc2 (ms)	446 ± 34	439 ± 34	0.53
value	0.26	0.002
Clinical parameters
K+ (mmol/L)	4.0 ± 0.4	4.1 ± 0.5	0.60
Na+ (mmol/L)	142.4 ± 5.0	141.5 ± 3.7	0.51
Cl− (mmol/L)	104.4 ± 3.8	104.1 ± 4.7	0.84
Cr (μmol/L)	69.7 (60.5–79.4)	75.0 (63.6–105.3)	0.19
UA (μmol/L)	327.4 ± 97.4	344.9 ± 105.5	0.58
BUN (mmol/L)	6.4 ± 2.0	7.1 ± 2.7	0.35

Data are expressed as mean ± standard deviation or median (P₂₅–P₇₅). QTc₁ means the QTc interval at baseline. QTc₂ represents the QTc interval at the end of the study. value at the end of the study compared with prior to drug administration in the AMIO group and the AMIO + WXKL group, respectively. AMIO = amiodarone; WXKL = Wenxin Keli; LAD = left atrial diameter; LVEDD = left ventricular end diastolic diameter; LVESD = left ventricular end systolic diameter; IVS = interventricular septum; LVEF = left ventricular ejection fraction; HR = heart rate; QTc = heart rate corrected QT interval; K+ = serum potassium; Na+ = serum sodium; Cl− = serum chlorine; Cr = serum creatinine; UA = blood uric acid; BUN = blood urea nitrogen.