Reduced Circulating Endothelial Progenitor Cells and Downregulated GTCPH I Pathway Related to Endothelial Dysfunction in Premenopausal Women with Isolated Impaired Glucose Tolerance
Table 1
Clinical and biochemical characteristics.
Characteristics
NGT (n = 20)
i-IFG (n = 21)
i-IGT (n = 20)
Age (years)
40.1 ± 5.3
41.2 ± 4.8
43.9 ± 3.6
Height (cm)
162.0 ± 7.6
163.1 ± 6.5
161.2 ± 5.9
Weight (kg)
61.2 ± 5.0
60.6 ± 6.9
61.9 ± 4.9
Body mass index (kg/cm2)
23.4 ± 2.1
22.8 ± 2.5
23.9 ± 1.8
Systolic blood pressure (mmHg)
121.2 ± 11.4
123.4 ± 7.8
121.9 ± 10.0
Diastolic blood pressure (mmHg)
71.7 ± 6.5
73.2 ± 5.4
70.7 ± 7.2
Heart rate (beats/min)
71.0 ± 6.3
73.8 ± 8.1
75.7 ± 8.7
Aspartate transaminase (mmol/L)
27.2 ± 6.1
25.5 ± 4.7
23.2 ± 4.6
Alanine aminotransferase (mmol/L)
25.6 ± 8.0
23.7 ± 4.6
22.6 ± 4.8
Blood urea nitrogen (mmol/L)
5.2 ± 1.3
5.0 ± 1.0
5.5 ± 0.9
Creatinine (mmol/L)
62.2 ± 19.0
60.6 ± 14.5
65.2 ± 15.7
Low-density lipoprotein (mmol/L)
2.80 ± 0.46
2.87 ± 0.44
2.99 ± 0.45
Total cholesterol (mmol/L)
4.80 ± 0.54
4.90 ± 0.56
5.04 ± 0.51
High-density lipoprotein (mmol/L)
1.43 ± 0.25
1.39 ± 0.24
1.35 ± 0.24
Triglyeride (mmol/L)
1.37 ± 0.22
1.42 ± 0.21
1.45 ± 0.20
Fasting plasma glucose (mmol/L)
4.81 ± 0.45
6.18 ± 0.38
4.96 ± 0.35
2-hour plasma glucose (mmol/L)
6.51 ± 0.62
7.14 ± 0.45
9.53 ± 1.04#
Glycosylated hemoglobin A1c (%)
5.30 ± 0.60
5.76 ± 0.49
5.91 ± 0.42#
Hypersensitive C-reactive protein (mmol/L)
1.15 ± 0.66
1.32 ± 0.71
1.44 ± 0.86
Estradiol (pmol/L)
237.4 ± 33.5
215.9 ± 37.4
202.1 ± 23.6
Flow-mediated brachial artery dilatation (%)
11.0 ± 1.41
9.63 ± 1.33
8.09 ± 1.36#
Abbreviations. NGT, normal glucose tolerance; i-IFG, isolated impaired fasting glucose; i-IGT, isolated impaired glucose tolerance. Notes. Data are given as mean ± standard deviation. vs. NGT; vs. i-IFG.