Biomarkers for Predicting Left Atrial or Left Atrial Appendage Thrombus in Anticoagulated Patients with Nonvalvular Atrial Fibrillation

Table 2

Laboratory parameters and echocardiographic parameters among the three groups.

Variable	No thrombus group (n = 84)	SEC group (n = 131)	Thrombus group (n = 45)	value
RBC (10^12/L)	4.55 ± 0.45	4.60 ± 0.49	4.77 ± 0.51^§	0.047
Hb (g/L)	142.49 ± 13.40	143.12 ± 15.16	145.75 ± 17.62	0.493
MCV (fL)	93.24 ± 4.03	93.30 ± 4.27	91.83 ± 6.23	0.165
MCH (pg)	31.37 ± 1.51	31.14 ± 1.53	30.59 ± 2.46	0.053
RDW (%)	12.76 ± 0.52	12.96 ± 0.64	13.19 ± 0.91^§	0.002
Plt (10^9/L)	214.83 ± 42.68	209.08 ± 47.77	224.20 ± 61.25	0.199
PCT	0.21 ± 0.04	0.20 ± 0.04	0.22 ± 0.05	0.321
PDW (%)	16.10 ± 0.63	16.12 ± 0.32	16.13 ± 0.30	0.910
PT (s)	12.43 ± 3.52	13.26 ± 4.17	14.54 ± 6.70	0.043
FIB (g/L)	2.80 ± 0.65	2.88 ± 0.74	2.84 ± 0.85	0.695
Urea (mmol/L)	5.77 ± 1.43	6.02 ± 1.93	6.02 ± 1.80	0.568
Cr (μmol/L)	74.86 ± 24.32	76.06 ± 27.83	75.87 ± 19.64	0.943
CK-MB (ng/mL)	10.33 ± 5.16	11.89 ± 8.26	11.24 ± 4.83	0.282
TC (mmol/L)	4.76 ± 1.16	4.88 ± 1.03	4.88 ± 1.40	0.725
TG (mmol/L)	1.85 ± 1.45	2.04 ± 1.85	1.97 ± 1.62	0.701
HDLc (mmol/L)	1.14 ± 0.24	1.13 ± 0.28	1.12 ± 0.31	0.905
LDLc (mmol/L)	2.92 ± 0.93	3.03 ± 0.80	3.02 ± 1.01	0.665
D-dimer (ng/mL)	414.87 ± 426.15	454.85 ± 538.92	503.48 ± 674.72	0.671
cTnI (ng/mL)	0.004 ± 0.007	0.004 ± 0.006	0.005 ± 0.007	0.443
NT-proBNP (ng/L)	373.91 ± 394.70	574.20 ± 548.28	1152.34 ± 997.06^§	<0.001

MCV = mean hemoglobin volume; MCH = mean hemoglobin content; RDW = red cell distribution width; Plt = platelet; PCT = lateletcrit; PDW = platelet distribution width; PT = prothrombin time; FIB = fibrinogen; urea = urea nitrogen; Cr = creatinine; CK-MB = creatine kinase isoenzyme; TC = cholesterol; TG = triglyceride; HDLc = high-density lipoprotein cholesterol; LDLc = low -density lipoprotein cholesterol; cTnI = cardiac troponin I; NT-proBNP = N-terminal pro-B-type natriuretic peptide. vs no thrombus group.^§ vs SEC group.