The Peroxisome Proliferator-Activated Receptor γ Agonist Pioglitazone Protects Vascular Endothelial Function in Hypercholesterolemic Rats by Inhibiting Myeloperoxidase

<div>Correlation analysis of MPO activity with vascular endothelial function, NOx content, and cGMP level in thoracic aorta rings between normal diet and HC diet groups. There was a positive correlation between MPO activity and the log EC50 value of ACh-induced vasodilation (a); ACh-induced maximum vasodilatation (b), NOx content (c), and cGMP level (d) showed negative correlation with MPO activity.</div>

Cardiology Research and Practice

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Figure 3: The Peroxisome Proliferator-Activated Receptor γ Agonist Pioglitazone Protects Vascular Endothelial Function in Hypercholesterolemic Rats by Inhibiting Myeloperoxidase

Figure 3 | The Peroxisome Proliferator-Activated Receptor γ Agonist Pioglitazone Protects Vascular Endothelial Function in Hypercholesterolemic Rats by Inhibiting Myeloperoxidase 