The Peroxisome Proliferator-Activated Receptor γ Agonist Pioglitazone Protects Vascular Endothelial Function in Hypercholesterolemic Rats by Inhibiting Myeloperoxidase

Table 1

Lipid profile in different groups (mmol/L).

Group	n	0 weeks			8 weeks
		TC	TG	LDL-CHO	TC	TG	LDL-CHO
Normal	12	1.44 ± 0.21	0.86 ± 0.21	1.44 ± 0.18	1.39 ± 0.16	0.65 ± 0.14	1.26 ± 0.37
HC	16	1.27 ± 0.32	0.82 ± 0.33	1.31 ± 0.27	3.12 ± 0.29	1.61 ± 0.36	2.38 ± 0.21
HC + DDS	16	1.32 ± 0.27	0.99 ± 0.27	1.29 ± 0.32	3.59 ± 0.38	1.78 ± 0.39	2.53 ± 0.45
HC + PIO	16	1.30 ± 0.39	0.77 ± 0.31	1.37 ± 0.29	1.56 ± 0.20^##	1.12 ± 0.29^##	1.68 ± 0.33^##

Values are expressed as mean ± SD. TC: total cholesterol; TG: triglyceride; LDL-CHO: low-density lipoprotein cholesterol; normal: normal diet group; HC: HC diet group; DDS: dapsone; PIO: pioglitazone. vs. normal diet group; vs. HC diet group.